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Calpains are a family of cysteine proteases, implicated in a wide range of cellular calcium-regulated functions. We elucidated the pattern of skin cleavage lines of the neck of Japanese cadavers and studied the scarring in 42 cases of radical neck dissection for the removal of metastatic nodules from the malignant tumors of the oral region, in the operation of which one incision was made parallel to, and another perpendicular to, the cleavage lines. Opiate modulation of monoamines in the chick forebrain: possible role in emotional regulation? The combination of congenital hearing loss and palmoplantar keratoderma, inherited as an autosomal dominant trait, led us to test for a mutation in the GJB2 gene in both patients. Donor site evaluation after autologous osteochondral mosaicplasty for cartilaginous lesions of the elbow joint.

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Methods for detecting genetic linkage are more powerful when they fully use all of the data collected from pedigrees. The CPG produces a side-to-side asymmetric pattern of intersegmental coordination among ipsilateral premotor interneurons corresponding to a similarly asymmetric fictive motor pattern in heart motor neurons, and asymmetric constriction pattern of the two tubular hearts: synchronous and peristaltic. Ethanol-induced inhibition of testosterone biosynthesis in rat Leydig cells: central role of mitochondrial NADH redox state. The local bone induction in the critical size of rabbit calvarial defects was evaluated six weeks post implantation. A magneto-optical microscope for quantitative measurement of magnetic microstructures.

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This proposal is used to illustrate how an effective verification scheme might be constructed. Receptor-interacting protein 140 overexpression impairs cardiac mitochondrial function and accelerates the transition to heart failure in chronically infarcted rats. Experiments using animal models of arterial thrombosis initiated by endothelial injury demonstrated that FucCS delivered as gastro-protective tablets produced a potent antithrombotic effect, whereas its aqueous solution was ineffective. Parotidectomy under sedation and locoregional anesthesia with monitoring of brain activity.

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Preoperative digital templating is a means to reduce the risk of intraoperative fracture, decrease overall surgical time, and plan for implant size prior to surgery. The mutant enzymes completely lost activity, suggesting that these residues play an important role in catalysis. Third, patients were cautious in making knowledge claims about their disease. Semisynthetic epsilon-isorhodomycins: their synthesis using glycals and their structure-activity relationship.

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Nevertheless repression of prdx-3 led to reductions in steady-state levels of ATP, motility, and brood size, indicating the importance of this enzyme to normal life in C. In some virus strains, a small amount of naturally occurring high and/or low density components were observed and these components were examined in more detail in one virus strain. The effect of movement-related information on the Corsi block tapping task. The CD74 expression was evaluated immunohistochemically and correlated to different prognostic variables.

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Comparison of two reflectance photometers in the assessment of neonatal hypoglycaemia. Severe hydrocarbon pneumonitis in African refugees after fuel ingestion. The findings from this study may indicate that predictive validity indices vary by the length of observation period and faller prevalence, but these findings need to be examined further. Dislocation locking versus easy glide in titanium and zirconium. The remarkable heterogeneity found between and even within countries, could be explained by several factors, importantly, socioeconomic and methodological aspects.

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Patients with substance use disorders (SUDs) prescribed long-term opioid therapy (LtOT) are at risk for overdose and mortality. The present pilot study explores the effects of acute administration of the beta-adrenergic antagonist propranolol on verbal problem solving in adults and adolescents with ASD.

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To clarify this relationship, we used in situ hybridization with biotin-labeled DNA probes of CMV and adenovirus (AV) in 40 patients with IgA nephropathy to determine the presence or absence of virus in affected renal tissue. We report a 1-year-old female child presenting with hypereosinophilia who was found to have concurrent myeloid sarcoma and a central nervous system (CNS) atypical teratoid/rhabdoid tumor (AT/RT). We evaluated HER2 results performed by immunohistochemistry and FISH in conjunction with ER, PR, and Ki-67 in 3093 invasive breast cancer cases from 2002 to 2011. Prioritizing HIV care and support interventions-moving from evidence to policy.

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A Global Consensus on Social Accountability for Medical Schools brought together 130 organisations and individuals from around the world with responsibility for health education, professional regulation and policy making to participate for 8 months in a three-round Delphi process leading to a 3-day consensus development conference which included weighted representation from all regions of the world. Child Abuse Mimic: Avulsion Injury in a Child With Penoscrotal Webbing. In addition, age appropriate sex-differentiated behavior was observed in social groups of treated infants at 5 and 11 months of age. A finite-element study of the effects of electrode position on the measured impedance change in impedance cardiography.

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The effectiveness of skin cancer screening and continuing medical education programs toward increasing the survival of patients with malignant melanoma. Palindromic rheumatism: part of or apart from the spectrum of rheumatoid arthritis.

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None of the patients had subjective post-operative disturbance in urination and the peak flow rate of post-operative uroflowmetry hardly decreased in 7 patients in whom this was performed. Therefore we hypothesized that MeHg-induced axonal degeneration might be caused by neuritic extension/retraction incoordination. To understand the structural alterations that underlie early and late changes in hippocampal diffusivity after hypoxia/ischemia (H/I), the changes in apparent diffusion coefficient of water (ADC(W)) were studied in 8-week-old rats after H/I using diffusion-weighted magnetic resonance imaging (DW-MRI). Fibronectin binding to Staphylococcus aureus in experimental staphylococcal skin infection in mice The chimeric receptors underwent autophosphorylation and induced the tyrosine phosphorylation of a specific set of cellular proteins in response to EGF.

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The paper present the biographical facts concerning A A Tardiue and characterizes the contribution he made to different field of forensic medicine in the middle of the XIX century including various forms of child abuse and neglect. Examination of the epidural space with lipiodol in the diagnosis of lumbosciatica

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Controlled-release of IGF-I and TGF-beta1 in a photopolymerizing hydrogel for cartilage tissue engineering. We address aspects related to the epidemiology, diagnosis, treatment and prognosis of this condition in males. IP-10 Is Elevated in Virus-Induced Acute Exacerbations in Childhood Asthma. We report that NexrutineR augmented the constitutively elevated oxidative stress markers in melanoma cells, which was abrogated by N-acetyl cysteine (NAC) pre-treatment.

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Tsunami disaster-stricken areas were defined as the 16 municipalities facing the Pacific Ocean in Miyagi Prefecture. The reaction of ascorbic acid with different heme iron redox states of myoglobin. Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases. An IS4 transposition causes a 13-bp duplication of phage lambda DNA and results in the constitutive expression of the cI and cro gene products. We report two siblings with isolated unilateral ectopia lentis who had no evidence of underlying abnormality or of trauma.

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In each case we recorded the responses to monocular stimulation (right and left), binocular stimulation and without stimulation (replicas of each condition). The value of lip strength measurements seems to be limited, due either to difficulties in recording lip strength or to a small influence of lip muscle forces on the dentition.

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The operations under intranasal endoscope for nasal septum malignant tumour have certainly indication. The results indicate that CRF and Ucn2 can modulate GnRH mRNA levels via each specific CRF receptor subtype. A circadian oscillator in these cells also raises and lowers melatonin output. Blind source separation of ex-vivo aorta tissue multispectral images.

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When taking into account measurement error, heritability estimates are substantial, but unique environmental factors continue to account for a large amount of variance in insomnia symptoms. Cloning and nucleotide sequence of the capsid protein and the nuclear inclusion protein (NIb) of potato virus A. Outcomes included clinic and ambulatory blood pressure, quality of life, left ventricular mass measured by M-mode echocardiography, left ventricular diastolic function measured by Doppler, and carotid atherosclerosis measured by beta-mode ultrasound.

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Studies on the oral route of nicotine administration in rodents make important contributions to our understanding of human nicotine use, and alternative approaches to smoking cessation. Hormones that influence the renal handling of calcium include parathyroid hormone, calcitonin and vitamin D. Peripheral gangrene during acute severe hypernatremic dehydration and disseminated intravascular coagulation in an infant Chronesthesia to cardiac glycosides of patients with cardiac failure.

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To evaluate the clinical effectiveness of subintimal angioplasty in treating chronic arterial occlusive disease of lower extremity. Posterior N1 to the distractor was reduced following a selective retro-cue compared to a neutral retro-cue condition, most notably at left hemispheric sites. Its unique characteristic is that the nodule localization is from the roof of the intercondylar notch. Ponatinib Induces a Persistent Molecular Response and Graft-versus-Host Disease/Graft-versus-Leukemia Effect in a Patient with Philadelphia-Positive Acute Lymphoblastic Leukemia with a T315I Mutation following Early Relapse after Allogeneic Transplant. Following a screening of 3416 articles, 38 primary research articles were identified.

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Live/dead viability/cytotoxicity assay was performed and analyzed by fluorescence microscopy after 24 hours of incubation. Indian boarding school experience, substance use, and mental health among urban two-spirit American Indian/Alaska natives. Future Class I and II evidence should be sought to evaluate the utility of stereotactic radiosurgery as a primary treatment modality or as an adjuvant for microneurosurgical resection of benign spinal lesions in patients who want noninvasive treatment after disease recurrence or who harbor medical comorbidities that would preclude them from being safe surgical candidates. MBL is a novel, independent diagnostic marker of DR in type 2 diabetic patients, suggesting that MBL may be involved in the pathogenesis of DR in diabetic patients. Even though the reason was still unclear, the results inspired us that only by diblock conjugates with improved cellular uptake can we realize tumor specific accumulation, deep penetration, and efficient tumor inhibition.

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This is the first qualitative study to specifically investigate the patient experience of dilator use. An update on the use of flow cytometry in HIV infection and AIDS. Genome-wide linkage analyses of type 2 diabetes in Mexican Americans: the San Antonio Family Diabetes/Gallbladder Study. Ventricular tachycardia (VT), a common manifestation of cardiac sarcoidosis (CS), is associated with high morbidity and mortality.