Letonal is a synthetic 17-Letonal corticosteroid with potassium-sparing diuretic, antihypertensive, and antiandrogen activities. Letonal competitively inhibits adrenocortical hormone aldosterone activity in the distal renal tubules, myocardium, and vasculature. This agent may inhibit the pathophysiologic effects of aldosterone produced in excess by various types of malignant and benign tumors. Check for active clinical trials using this agent.
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