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Mysoline (Primidone)

Mysoline is used for control of grand mal seizures that are refractory to other antiepileptics and seizures of psychomotor or focal origin. Mysoline is initially dosed in progressively increasing amounts starting with 100 mg at bedtime to 250 mg 3 times a day after 10 days of therapy in adults. Mysoline exhibits a volume of distribution of 0.6 L/kg and a half-life of 8 hours. When monitoring Mysoline and phenobarbital levels simultaneously, the specimen should be drawn just before the next dose is administered. Mysoline is not highly protein bound, approximately 10%. Phenobarbital is a metabolite of Mysoline. Like phenobarbital, there are no known major drug-drug interactions that affect the pharmacology of Mysoline. Toxicity associated with Mysoline is primarily due to the accumulation of phenobarbital. Diagnosis and treatment are as described for PBAR / Phenobarbital, Serum.

Other names for this medication:
Primidone, Mysoline,

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Genes encoding both enzymes were located on a single self-transmissible 100-kb plasmid, pOZ201. Alcohol consumption was reported on food frequency questionnaires and updated every 4 years. The abnormal life--potentially the death--of the cell can be restored by a metalloid--lithium--which is nearly as common as sodium in the mineral world. Systems for collaborative delivery of health care: governance seen as weak link. This report represents the first case of Lyme disease with possible valvular involvement.

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Operation times, lukewarm ischemic times and postoperative complications have been compared within the 3 groups. This inhibitory strategy might protect women without the need to preselect based on risk factors. We present software for an ensemble method that performs well in comparison with other methods regardless of the dimensionality of the data. Differences in enzyme activity between the three mouse strains were slight.

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Moreover, it has been shown that in certain conditions, Th17 cells can shift toward a nonclassic Th1 phenotype. We monitored the effects of stress on MDM2-dependent nuclear export of wild-type p53 and a mutant lacking N-terminal phosphorylation sites. Herein we report the outcome of a 2015 Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference where key issues in the management of these 2 diseases were considered by a global panel of experts. The oral cavity, mandible and neck of the nude mice were sectioned and examined histologically. The peripheral blood samples (5 ml blood for each sample) were from sensitive workers and resistant workers.

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It has been shown that segregational errors (SE) of chromosomes can be induced by olivetol and several halogenated inhalation anesthetics. Fatigue damage to pig erythrocytes during repeated swelling and shrinkage. Electrodiagnostic evaluation of diaphragmatic function has consisted of phrenic nerve stimulation and surface or esophageal recordings of the electrical activity of the diaphragm. We demonstrated the significantly increased risk of PAD in NASD patients through a nationwide population-based retrospective cohort study. Robotic surgery for atrial septal defect closure in a case of Kabuki syndrome.

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Inactivation of TRAPPII-specific subunits by various methods including siRNA depletion and CRISPR-Cas9-mediated deletion reduced lipolysis and resulted in aberrantly large lipid droplets. These domains develop in the same cortical locations across monkeys and humans, which raises the possibility of common innate mechanisms. Whereas cigarette smoking is an established risk factor, the effects of high alcohol intake and obesity are more uncertain. The 1990 data for 1,927 hospitals in 134 metropolitan statistical areas (with five or more hospitals) included Medicare fee-for-service risk-adjusted mortality rates from the Medicare Hospital Information Reports, hospital characteristics from the American Hospital Association annual survey, and HMO market penetration and competition calculated from InterStudy and Group Health Association of America data.

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Heat shock protein-90-beta facilitates enterovirus 71 viral particles assembly. Gangrene of the small bowel: a complication of methysergide therapy. Trends in the joint work of the National Center for Hygiene and the epidemiological hygiene inspectorates in the field of communal hygiene Several aspects of MS-related cortical reorganization, including the overall functional effect and likely modulation by therapies, still remain to be elucidated. To increase the success rate of Systematic Evolution of Ligands Exponential Enrichment (SELEX), the affinity of DNA pool in each round was simultaneously tracked using QCM in order to avoid the loss of high-quality aptamers.

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Minimal sets of walking assessments with comparable concurrent validity as all assessments together were proposed. Despite the importance of the axial skeleton in body support and locomotion, and much interest in the allometry of the appendicular skeleton, little is known about vertebral allometry outside primates. No major complaints and clinical complications during and after the treatment occurred.

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In acute pancreatitis, traditional treatment has been initial fasting on purpose to avoid activation of proteolytic enzymes and pancreatic enzyme secretion. The depth problem: identifying the most representative units in a data group.

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The developed photothermally controlled gene carrier has the potential for spatial and temporal site-specific gene delivery. Coordination of gastric and gallbladder emptying after ingestion of a regular meal. Fine-cut tobacco is a problem in both public health and consumer affairs. Group 2 consisted of 11 patients rejected for circulatory support because of renal insufficiency or infection (9), pulmonary embolus (1), and cerebrovascular accident (1). Complete resection of the hyperperfused regions is a strong predictor of favourable outcome.

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Multiplexed Quantification of Proglucagon-Derived Peptides by Immunoaffinity Enrichment and Tandem Mass Spectrometry after a Meal Tolerance Test. Implantation in rats treated neonatally with testosterone propionate. In this study, we investigated the impact of ER stress on intestinal epithelial barrier function using human colon carcinoma-derived Caco-2 monolayers. We studied long-term habituation of this reflex using two types of preparations, one focusing on the siphon component and the other on the gill component of the reflex.

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This lesion had appeared when she was 3years of age and no treatment was done. Artificial neural networks in the analysis of behavioral topology. Electrocardiographic identification of late potentials: a new noninvasive technique for identifying patients with ventricular tachycardia. Six patients complained of broadening in the middle nasal vault.

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The light intensity distribution was simulated to demonstrate strong dependency upon the slit array periodicity as well as wavelength and polarization of incoming light. The impact of an educational pamphlet on knowledge and anxiety in women with preeclampsia. The presence of GERD would, therefore, be expected to worsen nasal symptom scores. A systematic review of literature about Polygonum cuspidatum is carried out using resources including classic books about Chinese herbal medicine, and scientific databases including Pubmed, SciFinder, Scopus, the Web of Science and others. The effect of testosterone on the activity of ornithine decarboxylase (ODC), its protein level and immunocytochemical distribution were examined in the mouse kidney.

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Although their primary roles are different, they show striking similarities with respect to their features and additional functions. The protein has a predicted molecular weight of 108.6 kDa, and the isoelectric point is 8.106. Clinical risk assessment rating and all-cause mortality in secondary mental healthcare: the South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLAM BRC) Case Register. One of the major advantages of EUS guidance is the possibility of multiple access points depending upon patient and ductal anatomy. Emergency treatment of tracheal tear during pharyngolaryngectomy.

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To evaluate the costs of treatment and use of hospital resources when comparing routine abdominal CT and selective imaging practice based on clinical assessment in patients with acute abdomen. Several cancer prevention programmes have previously been executed using treatment of antioxidant compounds. OBS is a valid initial choice for selected patients without lymphoma-related symptoms. The C allele for rs1042522 in p53 was genetically associated with a higher risk for RD but not for PVR in this cohort.

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We detected no effect of pesticides on body weight, serum lipid, or lipoprotein cholesterol concentrations, or experimental atherosclerosis. Simulation results show that the UT-based method achieves accurate collision probability estimation and higher computation efficiency than MC and provides more valuable information concerning collision avoidance than the deterministic methods in the design of a pedestrian collision avoidance system. Avoidance of additional intravitreal vancomycin is recommended if HORV is suspected. However, cloud computing raises concerns on how cloud service providers, user organizations, and governments should handle such information and interactions. We used a Bayesian mixed effects multivariable logistic regression model to predict TB occurrence in either domestic or wild mammals per municipality in 2007 by using information from the previous year.

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Radiation-induced Sarcomas Occurring in Desmoid-type Fibromatosis Are Not Always Derived From the Primary Tumor. Peripheral ameloblastoma: report of case and review of the literature.

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For many identified PROMs there was no involvement of patients with OSA during their development or before the PROM was tested in patients with OSA. This was a cross sectional study based on recently collected data of 9077 Cutaneous Lishmaniosis patients (4585 female and 4492 male) from March 2003 to March 2011 in the Bam area, Iran.

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Only 8 cases of lung cancer and sequestration have been reported since 1963. We suggest that Nup170p and Nup157p may be part of a morphologically symmetrical but functionally distinct substructure of the yeast NPC, e.g., the nucleoplasmic and cytoplasmic rings. Parent and teen emotional problems are associated following adolescent TBI. Factor analysis was utilized to create an index using information about 11 symptoms of RTI/STI collected in the survey.

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Rectal temperature, skin temperatures and heart rate of the subjects were measured continuously during bathing and the subsequent 30-minute rest. The testosterone levels were as low as under treatment with DES.

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The same peptides (72 and 56 kDa) were also observed after incubation of the purified intact adhesin in diethylamine buffer. The mass was densely ossified without cortical destruction or other alteration in the adjacent calcaneal bone on x-rays and computed tomography images. Rather, continuity in prenatal care was associated with the observed increase in the number of prenatal visits, which in turn was shown to be a significant factor in the greater birth weights and maternal weight gain. Six new phenolic compounds, named smiglabrone A (1), smiglabrone B (2), smilachromanone (3), smiglastilbene (4), smiglactone (5), smiglabrol (6), together with fifty-seven known ones 7-63 were isolated from the rhizomes of Smilax glabra.

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Police-Recorded Crime and Perceived Stress among Patients with Type 2 Diabetes: the Diabetes Study of Northern California (DISTANCE). Experimental microalgae liquefaction without water index N was 0.6776, 0.3861 and 0.2856 for isolated lipid, protein and carbohydrate. Bone loss measurements from the mandibular posterior areas were representative of full-mouth bone loss measurements. Correlation between intensity fluctuations of electromagnetic waves scattered from a spatially quasi-homogeneous, anisotropic medium. Our results show no difference between the growth of these viruses in cells derived from juvenile diabetics and cells derived from nondiabetic siblings and parents even when the haplotypes were identical.

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Consensus was reached on a definition of a multisymptom outcome, the problem of source attribution, and the need for a hypothesis-driven conceptual framework to measure multisymptom outcomes. CD4 molecules with a diversity of mutations encompassing the CDR3 region efficiently support human immunodeficiency virus type 1 envelope glycoprotein-mediated cell fusion. Such exercises often convene evaluation panels to attempt a ranking of different stressors or stressor groups. Topiramate induces acute intracellular acidification in glioblastoma. The method is applied to the screening of a library of formate dehydrogenase mutants obtained by directed evolution.

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Antineutrophil Cytoplasmic Antibody-Positive Small-Vessel Vasculitis Associated with Antithyroid Drug Therapy: How Significant Is the Clinical Problem? Our finding provides some of the first evidence to support the long-standing belief that imprinting can occur in pink salmon prior to the PST.

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Minimally invasive plate osteosythesis of fractures of the radius and ulna in a primate. Using hydrogen-deuterium eXchange coupled to mass spectrometry, we obtained experimental evidences that the Trm11-Trm112 interaction relies on the same molecular bases as those described for other Trm112-methyltransferases complexes.

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Binding affinities of tyrosine-phosphorylated peptides to the COOH-terminal SH2 and NH2-terminal phosphotyrosine binding domains of Shc. A clinical registry can provide this information and subsequently support development of strategies to address any differences, including providing a platform for clinical trials. Genomewide identification of genes under directional selection: gene transcription Q(ST) scan in diverging Atlantic salmon subpopulations.

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Combined effects of interruption and interaural alternation on speech intelligibility. Analysis of the intracellular distribution of these chimeric polypeptides following transfection demonstrated a differential distribution of IL-1 alpha 1-112:beta-Gal in the nucleus and IL-1 alpha 113-271:beta-Gal in the cytosol.

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Recently, we have described the synthesis of chiral metal-organic frameworks iPr-ChirUMCM-1 and Bn-ChirUMCM-1 and their use in enantioselective separation. ANB and Wits must be included in 3D cephalometric analyses as both are necessary to undertake a more accurate diagnosis of the maxillo-mandibular relationship of the patients. This finding suggests disarranged or blocked intracellular transportation of proTGF-beta 1 in cancer cells. In addition, these case reports should influence the manner in which familial syringomyelia without tonsillar ectopia is defined and addressed, that is, posterior fossa decompression versus shunting of the syrinx, thereby addressing the potential cause of the syringomyelia and not only the enlarged cavity itself. Weather factors involved in outbreaks from 1975-88 were analysed to see if epidemics in Manitoba (23 or more cases in horses) could be predicted.

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We investigated behavioral problems, attention problems, and cognitive function in children and adolescents born small for gestational age (SGA). Continuous insolation heated the nucleus to greater depths than in other areas, producing the broad, active polar region. Effects of performance level on lower limb kinematics during table tennis forehand loop.

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Cytokines have now entered the clinical arena as important mediators of the immune system and the hematopoietic system. We furthermore established an absolute LC-ESI-MS/MS quantification method and demonstrate that absolute quantities of Gb4Cer correlate well with relative quantities obtained by indirect TLC-MALDI-TOF-MS. Stress-induced secretion of adrenocorticotropin, corticosterone, and prolactin in experimentally and genetically hypertensive rats.

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This was a retrospective review of 62 patients who had resection of retrorectal tumors between 2002 and 2010. Thereafter enamel protein production is impaired, leading to permanent enamel alterations. We compared the results of four population-based surveys performed in a town of Chorzow in 1993, 2002, 2007 and 2014 in children aged 7-10 years. However, which type of exercises are most beneficial to this subgroup is still unknown. KTP laser used at low power permits to obtain good pain control during operations that were carried out with only a topic anaesthetic (EMLA, Astratech), as shown in VAS tests.

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Those which do are small and unlikely to be clinically meaningful. The distribution varied for the different markers, CEA-positive macrophages being most abundant. The first breakthrough in its treatment came in 1922, with the discovery of insulin which was extracted from the pancreas of a dog. Calcineurin inhibitors versus cyclophosphamide for idiopathic membranous nephropathy: A systematic review and meta-analysis of 21 clinical trials.

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Comparison of structure of quinone redox site in the mitochondrial cytochrome-bc1 complex and photosystem II (QB site). Growth of femur from 9-day-old embryos that had been exposed to 6-AN for 5 days in ovo was not stimulated by PTH in an in vitro culture system. Three cores of tumor areas were punched out manually by using the mechanical pencil tips from donor paraffin embedded tissue blocks and transferred to the holes of the paraffin tissue microarrays.

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An epidemic of measles followed 2-3 weeks later in Beer Sheva district in Israel, initially among the Bedouin population just prior to the outbreak of the war, then spreading to the Jewish population. However, further experimental studies and, most importantly, prospective randomized clinical trials are warranted to prove new innovative concepts in clinical practice. This is the first study to demonstrate that 2-AB modulates glutathione homeostasis in the myocardium.

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A rapid increase in multidrug-resistant Gram-negative infections has led to a reemergence of colistin use globally. However, over the past few decades, clinicians have begun to utilize regenerative techniques to rebuild bone, cementum and the periodontal ligament. The effect of the thymus preparation thymalin (1000 micrograms/mouse, i.p.) on the system of cyclic nucleotides in the spleen has been studied. The morning hours are associated with increased cardiovascular (CV) risk, and vascular endothelial function (VEF) is a strong predictor of CV disease. To determine the effects of 12 weeks of resistance exercise training (RET) on disease severity and autonomic modulation at rest and after acute leg resistance exercise in women with fibromyalgia (FM) and healthy controls (HCs).

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Recent cytogenetic and molecular studies have demonstrated the loss of genetic material in this region. We did not identify any differences in TAP allele frequencies between those patients with atopic dermatitis and Japanese control subjects. A novel missense mutation, p.(R102W) in WNT7A causes Al-Awadi Raas-Rothschild syndrome in a fetus. The status of regional metastases in cancer of the uterine cervix in the second stage following combined radiation therapy Reaction energies are calculated, and we find that the thermodynamic favorability of the intermediate reactions is affected by the presence of steric constraints, oxygen coverage, and the exposed crystal surface of the metal.

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The lamellae consisted of several thin cytoplasmic processes of modified Schwann cells. Although programs differed in length, intensity, and training level of participants, all programs demonstrated improved team performance. In this paper the basic and clinical evidences concerning the effects of fish oil on these multifactors, which are deeply involved in the development of atherosclerosis are reviewed. This dose of allopurinol also caused a considerable fall in the clearances of 51Cr-EDTA and 125I-iodohippurate, normally used to measure glomerular filtration rate and effective renal plasma flow respectively.

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Here, we investigated reconstitution of antifungal immunity in patients during the first 12 months after HSCT and correlated it with IA. In response to the shortcomings of closed fracture manipulation, classic rhinoplasty techniques have been introduced to improve anatomic fracture quinobiot levofloxacino 750 mg reduction. The therapeutic strategy depends on several variables and requires for a patient-tailored approach mostly involving surgery.

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In the phase I trials, the reported maximum-tolerated doses were 790 mg/m2 to 1370 mg/m2 at the schedule of metronidazole triconex forte 30 minutes i.v. Other groups of compounds might be more suitable for the management of species-specific or sex-specific issues, as the effects of some compounds on particular rodent target species or sex might not be present in non-target species or in both sexes.

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The NDT80 gene product could be a component of the cell cycle regulatory machinery involved in the transition out of pachytene, a participant in an unknown aspect of meiosis sensed by a pachytene checkpoint, or a SPO11- and RAD50-independent component of meiotic chromosomes that is the target of cell cycle signaling. In rodents this period is neonatal, spanning the first weeks of life, whereas in humans it begins escitalopram withdrawal period of neomycin during the third trimester and continues 2 yr.

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A repeated measures ANOVA compared scores across the four measures, at three time points, for both tasks. It is the latter which contains the information of interest, and so it would be desirable to be able to estimate this function from a combination of the VEMP with some other data. Most clinical trial protocols zoloder capsule stain in Cameroon are developed to focus on benefits and pay little attention to harms. The natural vegetation in two low-Arctic meadow sites was manipulated. oxycoccana and the development of plant shoots from three cranberry and three highbush blueberry farms to determine whether the opportunity exists for successful movement of D.

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Disorders in the distribution of the activity of antioxidant defence enzymes, in the content of hydroperoxides and malonic aldehyde were discovered, with these disorders being diverse and dependent on the disease stage. The results showed high calcium plus VitD3 intakes considerably prevent biochemical and hepatic changes induced by HFHFr diet, probably via an insulin and AMPK-independent pathway. Plexiform fibrohistiocytic tumor: three unusual cases occurring in infancy. Suppression of the NK cell response by this treatment, however, was accompanied by enhanced becilan 250 mg solution injectable turkey spleen and pulmonary virus replication in vivo and increased susceptibility of mice to lethal infection. Expression was transient and highly localized to neointimal SMC during the proliferative and migratory phases of arterial injury, suggesting a possible role for osteopontin in these processes.

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Effect of methotrexate on basophilia in guinea pig sensitization. We compared these parameters both between groups and between different velocities. Use of a universal gas system for cryosurgery in treating oral cavity diseases Support for this was gained from studies with omeprazole capsule bp 20 mg cells from women who were treated successfully. Suppression of Canine Dendritic Cell Activation/Maturation and Inflammatory Cytokine Release by Mesenchymal Stem Cells Occurs Through Multiple Distinct Biochemical Pathways.

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Qualitative interviews with GPs and patients at three and nine months post-training will investigate experiences and challenges related to implementing recovery-oriented practice in primary care. The expression levels of prolyl oligopeptidase responds not only to neuroinflammation but also to systemic inflammation upon liver failure in rat models and cirrhotic patients. Phosphorylation of BlaR1 in Manifestation of Antibiotic Resistance in Methicillin-Resistant Staphylococcus aureus and Its Abrogation by Small Molecules. Intravenous microdialysis might help to obtain improved data sets as it is already successfully alain bexon clinical consulting done in small animals. The individuals without fluoride prevention formed the third group.

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In the spleen, adrenalectomy was associated with a significant up-regulation of type II receptors, which was blocked by the concurrent administration of aldosterone (1 microgram/h) via sc osmotic minipumps. At 20 and 30 days polymer degradation was evident and maxpro tablet in bangladesh current urothelial cells lined the polymer in continuous layers of 1 to 3-cell thickness. Effects of noise exposure level on the relationship between SNPs of SOD1 and the susceptibility to noise-induced hearing loss (NIHL) The method is validated for single and multi-echo acquisitions by experiments on a co-axial cylinder phantom with known macroscopic field disturbances. Therefore, SUMOylation of ARHGAP21 may represent a way of guiding its function.