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Piramax (Topiramate)
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Topiramate

Piramax is an anticonvulsant medication used in the treatment of epilepsy and migraine headaches. Piramax is also commonly used off-label to treat a wide range of mood disorders, eating disorders, and to aid in substance abuse therapy. While Piramax's mechanism of action is unclear, we know that the drug blocks sodium channels in the body that deliver electrical impulses to excitable cells (such as nerve, muscle, and brain cells). By doing so, Piramax appears to enhance the activity of a chemical messenger (neurotransmitter) known as gamma-aminobutyric acid (GABA).

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Pediatric reference values of carotid-femoral pulse wave velocity determined with an oscillometric device. Genomic sequence data of several hundred extinct and extant species allows for reconstruction of aGPCR phylogeny in vertebrates and non-vertebrates in general but also provides a detailed view into the recent evolutionary history of human aGPCRs.

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To assess the ability of proteins of the thrombospondin family to inhibit angiogenesis, recombinant murine thrombospondin-2, bovine thrombospondin-2/CISP and thrombospondin-5/COMP were purified and tested for ability to block the migration of capillary endothelial cells towards a variety of inducers and to inhibit neovascularization induced in the rat cornea. Contrary to physical intuition, in general the polarization eigenstates in such three-dimensional and low-symmetry metamaterials do not obey fixed relations and the associated transmission matrices cannot be symmetrized. The above results encourage clinical development of NVP-BEZ235 in combination and the possible inclusion of patients with mantle lymphoma in Phase I/II clinical trials.

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The effects on uterine growth and gonadotrophin release were tested and compared to oestradiol or vehicle alone. An epidemiological survey of the prevalence of thyroid diseases in mild iodine deficiency city after salt iodization Do we need controlled attenuation parameter adjustment for fibrosis estimation in nonalcoholic fatty liver disease patients? Plasminogen activator inhibitor 2 reduces peritoneal fibrinolytic activity in inflammation. Isolation and characterization of a novel dithio-carbodenafil analogue from a health supplement.

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Overall, our results suggest that RIL has not only direct effect on circulating lymphocytes, but also has indirect effect on circulating lymphocytes as well as stem cells in the nonirradiated BM. Caco-2 cells of passage number 181-183 were found to lack endopeptidase-24.11, but maintained dipeptidyl peptidase IV expression. Resting and Activated Natural Tregs Decrease in the Peripheral Blood of Patients with Atherosclerosis. The pancreatic stellate cells strength are involved in collagen production during acute pancreatitis and why antihypertensive drugs such as lisinopril and losartan may possibly have beneficial effects in reducing pancreatic fibrosis in models of experimental obstructive pancreatitis.

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Certain hair cells of fish exhibit strong immunoreactivity to an S-100 antibody. We compared direct cost savings and TAT for blood availability with historical data before we began phenotyping.

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Reproduction in wild gorillas and some comparisons with chimpanzees. Key role of phosphoinositide 3-kinase class IB in pancreatic cancer.

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The fission yeast Schizosaccharomyces pombe carries a gene, named spk1, whose product is structurally related to vertebrate MAPK. Intervention studies were assessed against the Cochrane Effective Practice and Organisation of Care methodological criteria, and papers meeting criteria were assessed for quality.

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Austrian national carotid intervention numbers prompt improvement in secondary stroke prevention. Familial hypobetalipoproteinaemia (FHBL) is a rare monogenic cause of hypocholesterolaemia.

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Development and characterization of 29 polymorphic EST-SSR markers for Stipa purpurea (Poaceae). Obese women, 17 from an eating disorders program and 60 from a primary care setting, were administered the borderline personality scale of the Personality Diagnostic Questionnaire--Revised, the Diagnostic Interview for Borderline Patients, and the Self-Harm Inventory.

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Comparative morphological and molecular studies indicated that the new taxon belongs to a group that also comprises species of the stalk-forming anamorphic genera Fellomyces and Kockovaella. Our results from a population-based study suggest that myopic status is associated with lower odds of having diabetic retinopathy in the South Korean population. Uncritical use of tranexamic acid in trauma patients : Do no further harm Overall, the present study sets the basis for potential emotional mechanisms that could explain how cultural symbols can act as extensions of the prototypical attachment figures and confer the sense of security in the face of threat.

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Current provisions of neighbourhood green space may be more amenable to promoting active lifestyles among boys than girls. The avidin-biotin-peroxidase complex (ABC) method was applied to semithin (0.5-1 micron) plastic-embedded sections of intact male rat pituitaries with the use of techniques previously developed for the peroxidase-antiperoxidase complex (PAP) method. The objective of this systematic review is to determine the effectiveness of interventions with empowerment concept for chronically ill patients.

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However, clinical data identifying the benefits of IG-IMRT in daily practice are scarce. No similarity was found among bat trypanosomes and Trypanosoma (Schizotrypanum) cruzi standard zymodemes. A new strategy of photoelectrochemical analysis without an external light source based on isoluminol chemiluminescence probe.

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Retinoblastoma regression patterns and results following chemo reduction and adjuvant therapy The paper reviews the current situation of mentally ill individuals and barriers to enter the open labour market. Linear lichen planus and lichen striatus--opposite ends of a spectrum. This should be studied in greater detail, but these results can contribute to a deeper understanding of the complex Colombian social context.

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Role of angiotensin II in the physiologic regulation of glomerular filtration. These procedures test whether the designed protein will indeed be alpha-helical, well packed and stable over a time scale of several nanoseconds in a realistic lipid bilayer environment.

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Private sector involvement in times of armed conflict: What are the constraints for trading medical equipment? Amlodipine or lisinopril was not better than chlorthalidone in reducing renal outcomes in hypertension and impaired renal function.

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Solid organ transplant (SOT) recipients are often heavily immunosuppressed and consequently at risk of serious illness from vaccine preventable viral and bacterial infections or with endemic fungal and parasitic infections. Therefore, GA-DDAB may be a more cost-effective and efficient antimicrobial agent than others in use today. A single-blinded radiologist used a surface shaded three-dimensional endoluminal fly though and two-dimensional axial and multiplanar reformats to assign a score for maximum polyp size and number based on the Spigelman classification. Exercise capacity of postmenopausal women may be influenced by sex hormones, which levels in blood could be useful in the qualification for physical recreation plan.

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Plant cells have two main modes of growth generating anisotropic structures. To validate a shortened version of the Physical Self-Concept Questionnaire (PSQ-S) and verify its ability to discriminate between people with different levels of EBD. The zinc sulfate and placebo were administered beginning on the first day of radiation, and continued daily including weekends until radiation was completed Patients were evaluated before radiation, weekly during radiation and at the first month after completion of radiation. Representative scientific publications were chosen from searches using the NCBI PubMed and ISI Web of Knowledge databases. Visual analgoue scale (VAS), Oswestry-Disability-Index (ODI), vertebral height and kyphosis angle were assessed preoperatively, 3-4 days, 3 and 6 months postoperatively.

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Nitric oxide production and the expression of two nitric oxide synthases in the avian retina. While telemedicine is beginning to Hower, there are numerous barriers that prevent its rapid implementation, such as licensure, reimbursement, liability, quality of service, and technical issues. Chiral twist drives raft formation and organization in membranes composed of rod-like particles.

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Taking into account the species dispersal among nearby connected habitats (or patches) through a common dynamic environment, we model the consumer-resource interactions with a ring type coupled network. Focal diastasis in the treatment of fractures with extrafocal fixation devices The study included 50 patients (50 eyes) with unilateral BRVO and 35 control subjects (35 eyes). A survey of copper levels in agricultural soils of central Chile revealed two soil clusters-one with a mean copper level of 162 mg/kg and one with a mean copper level of 751 mg/kg of soil. Severe Combined Immunodeficient (SCID) mice reconstituted with human peripheral blood leukocytes (PBL) develop fatal B-cell lymphomas of human origin following latent or active infection with EBV.

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Recent findings have highlighted the importance of clinical investigations in patients with achondroplasia, differentiating between those that look for neurological patterns and those that look for respiratory problems during sleep. The confidence ratings of diagnoses of simulated lesions other than lung cancer on low-dose CT screening were not degraded with hybrid IR compared with FBP.

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A spin echo echo planar imaging protocol was used in conjunction with multiple bolus injections of the susceptibility contrast agent gadoteridol (GD). A primary cell culture system of luteinizing hormone releasing hormone neurons derived from embryonic olfactory placode in the rhesus monkey. Some 4-thiazolidinone derivatives containing indolin-2-one moiety are novel anti-tumor compounds.

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The population sampled from the Wantoat River Valley included 72 males and 38 females with 12 male cretins. This study developed and tested a moderated-mediation model of work stress and alcohol use, based on the biphasic (stimulant and sedative) effects of alcohol and the self-medication and stress-vulnerability models of alcohol use. We describe the management of steroid-induced glaucoma with ExPRESS mini-shunt in a 9-year-old boy with allergic keratoconjunctivitis.

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Renal tissue MDA levels were significantly lower in the control and Vit E groups compared to that of the CRF, Vit A and Vit D groups. We retrospectively compared the intra- and postoperative blood loss, morbidity, mortality, blood transfusion requirements and hematologic findings in the ASA group (40 patients) and the control group (62 patients). A control experiment using rapid serial visual presentation suggests that it is the greater horizontal compression and consequently reduced eye-movement requirements of variable pitch that are responsible for its superiority at medium and large character sizes.

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Therefore, for ABR recordings to be reliable, noise must be minimized and appropriate evaluation of waveform changes is critical. Perceptual specificity along an acoustical dimension affecting behavioral inhibition.

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We have isolated a cloned segment of Drosophila genomic DNA containing a ribosomal protein gene. To investigate the expression of transfected human endostatin (hES) gene in tongue squamous cell carcinoma (TSCC) and its inhibitory effects on the growth of tumor cells in vivo. The effects of cycloheximide on MHV-specific RNA synthesis were determined. Caspase-12 dampens the immune response to malaria independently of the inflammasome by targeting NF-kappaB signaling. The influence of genetic factors on intended caregiving responses to infant crying is substantial for normal variations in sensitive caregiving, but absent for harsh caregiving responses.

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Sites of dissolved organic matter (DOM) accumulation could promote the mixotrophic nutrition of Trichodesmium when inorganic nutrients are scarce. Lithium is still regarded as a cornerstone for the long-term treatment of bipolar disorder.

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An artificially constructed hairpin terminus was unable to stabilize a linear plasmid in yeast. Spiroborate esters in the borane-mediated asymmetric synthesis of pyridyl and related heterocyclic alcohols. We would recommend close monitoring of full blood counts after instituting azathioprine therapy but would question the cost-effectiveness of pretreatment TPMT activity in pediatric practice.

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Using the profile analysis, the density perturbation transport analysis, and the Doppler reflectometry measurement, for the first time a spontaneous and steady-state particle-transport barrier has been evidenced in the Ohmic plasmas in the HL-2A tokamak with no externally applied momentum or particle input except the gas puffing. The surgical treatment and orbitocranial mesh reconstruction following neurosurgical gross total removal of the lesion is discussed.

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Muscle forces during driving are not currently known, yet knowledge of these would influence important clinical advice such as return to activities after surgery. Part 2: Three-dimensional measurement of intralobular structures Gender differences in the availability and use of family support may partly account for the gender disparity of LTC discharge and post-discharge living arrangements.

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We have studied cell lineage by using this method in the following ways. Newly synthesized GQDs exhibited a strong blue photoluminescence (PL) under 365 nm UV light illumination. Crowdsourcing is an effective approach to quickly and economically collect a large reliable dataset of normative natural language responses.

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We aimed to evaluate the effects of different PEP and CPAP devices on IC as an indirect measure of induced changes in FRC from these devices in healthy subjects. Study of the circulation of the red blood corpuscles and of plasma in human cerebral blood vessels The vitamin hormone retinoic acid (RA) regulates many complex biological programs. These mechanical inputs, which may be encoded in the form of extracellular matrix stiffness, dimensionality, and adhesion, all strongly influence cell morphology, migration, and fate decisions.

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Five-Year Outcome After Implantation of Zotarolimus- and Everolimus-Eluting Stents in Randomized Trial Participants and Nonenrolled Eligible Patients: A Secondary Analysis of a Randomized Clinical Trial. Data analysis involved inductive coding to identify emergent themes and deductive contextualization to make meaning from the emergent themes. As evaluation of Langerhans cell histiocytosis patients with F-18 FDG PET/CT is becoming more frequent, it is important to be aware of the scintigraphical characteristics of thymic Langerhans cell histiocytosis. Further studies investigating their role as potential risk factors are warranted. Day case oral surgery: a review of 25 years experience at the Dublin Dental Hospital.

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Conversely, of the recombinant viruses in the DKGX/22 background, only the one that contains the PB2 gene of DKGX/35 was able to replicate in mice. Currently, treatment approaches are based only on adult data, and problems exist in extrapolating these data to a pediatric population. The amino-terminal sequence of the MOMP showed considerable similarity to those of porin proteins from other gram-negative bacteria.

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Update: adverse events associated with anthrax prophylaxis among postal employees--New Jersey, New York City, and the District of Columbia metropolitan area, 2001. These results support a hypothesis that debridement with CCO is associated with decreased inflammation and greater progress toward healing. Blood group is an important risk factor for some malignancies, including pancreatic and stomach cancer. The possibility of using unmodified ligands in the study of biological activities of protein substructures while consuming very little material makes CE further attractive.

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Enhancement of Cd phytoextraction by hyperaccumulator Sedum alfredii using electrical field and organic amendments. Prospective study on the occurrence and management of chronic sinoatrial disease, with follow-up.

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The treatment options for negative symptoms are extremely limited. We apply the method to four different starting states: a straight rod, two rods containing either one or two 20 degrees bends, and a circular O-ring. One hundred and eighteen B19V-DNA positive source plasma pool samples collected from three Chinese blood products manufacturers were analyzed. Pairwise comparison of orthologous olfactory receptor genes between two sympatric sibling sea kraits of the genus Laticauda in Vanuatu. Epidemiological studies have shown that pregnant women continue to take substantial quantities of drugs, particularly those readily available to them without prescription.

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The results obtained represent the basis for the complete structural characterisation of the modified haemoglobin and demonstrate the usefulness of the proposed analytical approach for the evaluation of alkylation degree and the identification of modified amino acids in proteins. Characterizing the inhibitory action of zinc oxide nanoparticles on allergic-type mast cell activation. An important factor is the overexpression of efflux pumps, such as P-glycoprotein. This retrospective study used a large administrative claims database covering 8 million insured lives in the US from 1999 to 2006. Tuberous sclerosis complex (TSC) is an autosomal dominant disorder with multi-system involvement and variable manifestations.

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Paradoxical activation by glucose of quinine-sensitive potassium channels in the pancreatic B-cell. Using published fetal human RNA-seq data, we show that the gene-neighborhood (i.e., microsynteny) of long intergenic non-coding RNAs (lincRNAs) implicated in cortical development is differentially conserved in large-brained species, lending support to the hypothesis that lincRNAs regulating neurogenesis are selectively lost in small-brained species.

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This association may prove relevant for early disease recognition based on a quantitative structural characterization of CH patterns. The first patient, a 56-year-old woman, was diagnosed as having chronic progressive ataxic sensory neuropathy.

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Therefore, in order to examine the evolutionary history of the complex within Diptera, we reconstructed, using several fosmid clones, the entire E(spl)-complex in the stalk-eyed fly, Teleopsis dalmanni and collected additional homologs of E(spl)-C genes from searches of dipteran EST databases and the Glossina morsitans genome assembly. Otherwise, the danger could be that the current relatively low smoking prevalence among university students may dasabuvir mechanism of action escalate in the future. Temporomandibular joint function and its effects on concepts of occlusion. To better characterize brain circuits dysfunctions in normoacousic tinnitus sufferers.

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We investigated the association between global, regional, and hemifield differences in retinal nerve fiber layer measurements and visual field loss with linear regression techniques. The 49 female soldiers observed in the field studies had suboptimal mean energy (1751 citalopram teva 20 mg pris kcal), protein (52.3 g), calcium (620 mg), and iron (11.8 mg) intakes.

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We conducted a secondary analysis of data from the National Survey of Family Growth 2011-2013, a population-based survey of U.S. Each tool utilized four risk categories and reflected levofloxacin dose in typhoid level of development and medical capabilities. Interestingly, human miR-1271 is expressed abundantly in brain tissue, where miR-96 is not highly expressed. Based on the MR analysis, the risk of cerebral ischemia-hypoxia during clamping was classified as high, moderate and low. Early brain injury, one of the most important mechanisms underlying subarachnoid hemorrhage (SAH), comprises edema formation and blood-brain barrier (BBB) disruption.

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The mechanism of bula moxilin 500 mg to grams the antiinflammatory activity of 2-(5-ethylpyridin-2-ly)benzimidazole (KB-1043), a new benzimidazole derivative with antiinflammatory, analgesic and antipyretic activities, is described. Proton transfer between dimers is associated with strong bases and very good hydrogen bond donors, namely, between very different chemical species. Although salivary gland neoplasia has been associated with a history of radiation therapy during childhood, acinic cell carcinoma in such a setting is rare. Each flap survived completely with no complication other than partial dehiscence in one case and temporary postoperative discomfort and pain upon sitting.

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The time course of expression of transfected genes in nontransformed cell types with low mitotic indices, such as type II cells, is poorly denoral posologie citrate characterized. Infection with Plasmodium Falciparum can cause a severe form of malaria with multiorgan involvement.

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Urologists, surgeons, and emergency physicians should be aware of this rare complication of atypical acute acyclovir 800 mg five times a day abbreviation appendicitis. Diagnosis of periodontal diseases using different classification algorithms: a preliminary study. We are pursuing a new approach: restoration of function by electrical activation of higher-order interneurons.

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Assessment of amylase and lipase levels following puncture biopsy and fine needle esomeprazole 20 mg indicaciones ciprofloxacino aspiration guided by endoscopic ultrasound in pancreatic lesions Parathymic lymph nodes as potential sites of tumor progression have been neglected in humans.

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This in turn suggests the importance of cytoplasmic maturation for embryonic development. Acetylcholinesterase activity in regions of rat brain lamitor od 100 side effects following repeated administration of electroconvulsive shock. The effects of black widow spider venom on the innervation of muscles paralysed by botulinum toxin.