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Purinase (Allopurinol)
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Allopurinol

Purinase is used for treating gout caused by excessive levels of uric acid in the blood (hyperuricemia). It is a xanthine oxidase inhibitor and is similar to febuxostat (Uloric). Uric acid is a by product from the breakdown of certain proteins (purines) in the body by enzymes called xanthine oxidases. Hyperuricemia occurs when the body produces more uric acid than it can eliminate. The uric acid forms crystals in joints (gouty arthritis) and tissues, causing inflammation and pain. Elevated blood uric acid levels also can cause kidney disease and kidney stones. Purinase prevents the production of uric acid by blocking the activity of the enzymes that converts purines to uric acid. Uric acid levels usually begin to fall within 2-3 days of starting treatment and return to their original levels within 7-10 days after Purinase is stopped. It may take several months of therapy before attacks of gout are controlled. The FDA approved Purinase in August 1966.

Other names for this medication:
Allopurinol, Zyloprim, Allosig, Allupol, Aloc, Alomaron, Alopron, Aluron, Darinol, Goutex, Llanol, Loric, Prodec, Puribel, Puricos, Purinase, Purinol, Talol, Tipuric, Uriprim, Zurim,

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Regulatory elements in the promoter region of the renal kallikrein gene in normotensive vs hypertensive rats. Repression and activation of the genome of herpes simplex viruses in human cells. Postoperative color Doppler sonography of the ureteral jets to detect ureteral patency in laparoscopic hysterectomy. We show that WIT2, but not WIT1, plays an essential role in nuclear shape determination by recruiting myosin XI-i to the SUN-WIP NE bridges.

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