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The response rate and toxicity of the domestically made topotecan are comparable with those of the imported one. Moreover, it is likely that polar metabolites of 1,25-dihydroxyvitamin D3 present in the bile of rats in vivo are formed in the liver. The membrane-proximal external region (MPER) of HIV-1 gp41 is recognized by all three anti-HIV antibodies 2F5, 4E10 and Z13 that were directly derived from AIDS patients and have broader anti-HIV neutralizing activities. Changing concepts of the junctional nevus and melanoma: review of the literature and report of case. The results in the hypertensive group were compared with those of a control group consisting of 11 normotensive women aged between 21 and 46 years who had earlier taken part in an identical experiment.

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This cross-sectional study examined relative associations between exposure to violence in 3 different contexts (home, school, community) and depressive symptoms, using data from 233 11th-graders (predominantly economically disadvantaged Hispanic and African American students). Hair removal with a combined light/heat based photo-epilation system.

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Consequences of obstructive sleep apnea on metabolic profile: a Population-Based Survey. Implants may be divided into mono- and multi-electrode and into intra- and extra-cochlear.

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Electron transport chain (ETC) activity is not altered in PD in this well-characterized cohort when compared with community-matched controls but appears to be affected by environmental toxins, such as mitochondria-inhibiting pesticides. Ubiquitin may be involved in the cellular activity of LH cells in the rat pituitary.

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Since there were no scientific data to support the above claims, the present study was therefore undertaken to assess estrogenic properties of Cameroonian propolis. A very large left ovarian tumor in a 76 year old woman, on microscopic study, consisted of an epithelial component: both glandular and squamous, and a sarcomatous component: both cartilage and striated muscle. Each L1 gene contained 3944 nucleotides and was 10 bases shorter than the previously reported L1 gene of BTV 10. The purpose of this study was to demonstrate the effects of the tight junction permeation enhancer, AT1002, on the nasal absorption of molecular weight markers and low bioavailable therapeutic agents co-administered with bioadhesive polymers or zonulin antagonist.

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The ideal model of liquid chromatography in gradient elution was solved by using the characteristic approach on the assumption of a linear solvent strength model. Many children seen in these EDs were eligible for measles vaccination, and many eligible patients were not vaccinated. Present status of the curriculum in Japanese dental universities Development and Validation of the Good Outcome Following Attempted Resuscitation (GO-FAR) Score to Predict Neurologically Intact Survival After In-Hospital Cardiopulmonary Resuscitation. To mimic these conditions, Lactobacillus plantarum was grown in a carbon-limited retentostat with complete biomass retention.

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Adult second language learning seems to be more difficult and less efficient than first language acquisition during childhood. This can be affected by several factors, one of which is the heat generated in the acrylic cement, which may exceed the level at which tissue viability is affected. Methodological and possible publication bias could result in sex-biased medical practice. When integrated at the whole-canopy scale, the model predicted that raising N availability above an NNI of 1 did not result in increased net photosynthesis. Policy interventions should therefore not only consider health risks posed by unemployment, but should also aim at the reduction of insecure employment.

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There are limited data concerning the clinical details and outcomes of patients treated in this manner. Surface-related parameters that may affect hydroxyapatite nucleation are discussed in terms of the electrical double layer. Characteristics and Survival Determinants in Patients After Out-of-Hospital Cardiac Arrest in The Era of 24/7 Coronary Intervention Facilities. However, the literature does not provide coherent analyses of how these ambitions can be achieved. The accuracy of computed tomography to predict completeness of pulmonary fissures.

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Histological pulp changes in the dental osseous segment following anterior maxillary osteotomy. Quantitative proteomic analysis of microtubule pull-downs, using ratiometric (14)N/(15)N labeling, revealed 605 proteins exhibiting differential accumulation during TE differentiation. We analysed datasets from four recognition memory studies on same- and cross-race faces to test this hypothesis. The present study examined the effects of gender, video game experience (VGE), and flow state on multiple indices of combat identification (CID) performance.

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A relatively-selective increase in either ethane or pentane was observed when either linolenic acid or linoleic acid, respectively, was added to tissue homogenates. Prevalence of cutaneous leishmaniasis along the Nile River north of Khartoum (Sudan) in the aftermath of an epidemic in 1985. Public policies and cost-effective interventions are needed to improve both access to treatment and quality of treatment. In this paper, characteristics of the material being sensed and magnetic properties of the ferromagnetic polymers will be discussed.

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No reactivity was observed between deoxythymidine and the sugars. Nucleic acid testing by public health referral laboratories for public health laboratories using the U.S. Femoral avulsion fracture of ACL proximal attachment in male scuba diver: case report and review of the literature. This study sought to measure the extent of respiratory gas change during this procedure. Nonetheless an understanding of the psychosocial profile of these athletes complements the extant physiological and technological knowledge in enabling a holistic view of what contributes to the successful Paralympic athlete and may facilitate the team working to optimize performance and wellbeing in these high-performing individuals.

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The frictional aging at the nanoscale may result from nucleation of capillary bridges and strengthening of chemical bonding, and it imposes serious constraints and limitations on the performance and lifetime of micro- and nanomachines. Talonavicular ligament: prevalence of injury in ankle sprains, histological analysis and hypothesis of its biomechanical function. Systemic antiinflammatory corticosteroid reduces mechanical pain behavior, sympathetic sprouting, and elevation of proinflammatory cytokines in a rat model of neuropathic pain.

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Acute pharyngitis presenting to the pediatric emergency department can be managed in accordance with the recommendations in the Scottish Intercollegiate Guideline Network guideline. The development of evidence-based interventions should be a priority.

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With high efficacy and bacterial eradication rates, good tolerability and convenient once-daily administration, telithromycin therapy should result in increased patient compliance and improved outcomes, thereby minimizing the risk of developing antibacterial resistance. Patients with abnormal CDP results and/or complaints of vertigo underwent follow-up CDP when healthy. Thrombin formation and effect of unfractionated heparin during pediatric cardiac catheterization. Hybrid natural orifice transluminal endoscopic surgery (NOTES) nephrectomy has been reported by a few groups in the last two years. The examinations were reviewed for the type of ACL injury, secondary imaging findings, and associated knee injuries.

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These findings, if proven, may be indicative of chronic forms, thus guiding more accurate treatments and guiding clinicians through more accurate prognosis. The effect of periodontal therapy on the glycemic control of older uncontrolled diabetics will require further studies that will have to include much larger sample sizes. Spinal epidural abscess is a rare condition that can lead to irreversible complications and death if untreated.

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Primary mCPC detection outperformed the use of percent free PSA and the Montreal nomogram in predicting clinically significant PC at initial PB. This hypothesis was validated by in vitro hCES1 inhibition studies. Nuclear Factor Y (NF-Y) was first described as one of the CCAAT binding factors.

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However, this increase seemed insufficient to match aortic root size, particularly in central AR, whereas in eccentric AR, there was relative abundance of cusp tissue resulting in relative cusp prolapse. Single-molecule photon-stamping spectroscopy correlated with electrochemical techniques was used to dissect complex interfacial electron transfer (ET) dynamics by probing an m-ZnTCPP molecule anchored to a TiO2 NP surface while electrochemically controlling the energetically-accessible surface states of TiO2 NPs. Hydrocortisone was shown to prompt the accumulation of pancreatic enzymes taking part in the processing of food protein components in food-deprived chicks.

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The validity and inter-tester and intra-tester reliability of a digital inclinometer for measuring knee JPS were assessed. Here we summarize recent advances in understanding of the biology of BCL2 family members that shed light on the action of BH3 mimetics, review preclinical and clinical studies leading to the regulatory approval of venetoclax, and discuss future investigation of this new class of antineoplastic agent. In a retrospective study of patients in the ICU, administration of PPIs to prevent bleeding was not associated with increased risk of BSI. Magnetic recordings of the test samples were evaluated by a panel of nine listeners. Immediate deflation of pneumoperitoneum and atropine administration are effective measures that may alleviate bradycardia and possibly avert progression to cardiac arrest.

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The amount of PLAP mRNA began to increase dramatically around 13th week and probably continued to increase gradually until term. Quantum discord, a measure of genuinely quantum correlations, is generalized to continuous variable systems. This article examines the use of crisis intervention through moral duties, intentions and consequences, culminating in an action/consequence model of risk management, used to explore potential outcomes. We studied the number of units by recipient, the characteristics of recipients, the results of blood tests performed after transfusion, the incidents in donors and recipients, the period for obtaining a unit of FWB and mortality of recipients.

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Women hospitalized with a diagnosis of PTL during a 3-year study period were identified within a health maintenance organization. In particular, diets enriched with linoleic acid have been consistently found to be effective in enhancing the metastatic potential of murine mammary tumors.

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Ethnic minority position is associated with increased risk for psychotic outcomes, which may be mediated by experiences of social exclusion, defeat and discrimination. We show that inhibitory control processes are impaired when the working memory load surpasses a certain threshold. At the time of resection, MC had metastases (Stages C and D) more frequently then non MC (P less than 0.02).

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Although patients with BEB and HFS present clinically with involuntary movements of facial muscles, they exhibited differences in cortical thickness. Direct evaluation of DLVO theory for predicting long-range forces between a yeast cell and a surface. Practical implications of the lumbar spine and its function on total hip arthroplasty. Effects of steroid therapy on long-term canal prognosis and activity in the daily life of vestibular neuronitis patients In direct opposition to this model, we find that neither nonmuscle myosin-II nor RhoA appear to function in PS2 clustering.

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Control experiments with defined fatty acid mixtures reveal the complexity of the cellular response to assault by combinations of lipids. Careful consideration of ethical aspects demands the further evaluation of whether or not the patent is an adequate tool for regulating these matters. Dominant mutations in five tRNA synthetases cause Charcot-Marie-Tooth (CMT) neuropathy, suggesting that altered aminoacylation function underlies the disease. The importance of visualizing both the dorsal and ventral pancreatic ducts to direct therapy for patients with idiopathic pancreatitis is discussed. The purpose of this article is to present the CT findings in 55 cases of tarsal navicular stress fracture before and after treatment and to describe the CT protocol used.

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The influence of pH, peroxynitrite concentration and temperature on the pseudo-first-order rate constants was studied and the activation energy calculated. The Mr 48,000 host tumor antigen (48,000 HTA, also called nonviral T Ag) is preferentially complexed with the maximally phosphorylated T Ag. Effects of cyclic AMP on S-100 protein level in C-6 glioma cells. P300 potential may be a complementary method in the diagnosis of hepatic encephalopathy. The Comprehensive Osteopathic Medical Licensing Examination conducted a trial of multimedia items in the 2008-2009 Level 3 testing cycle to determine (1) if multimedia items were able to test additional elements of medical knowledge and skills and (2) how to develop effective multimedia items.

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Fat randomization and interesterification change triacylglycerol (TAG) structure and its solid fat content profile. Furthermore, in the objective of performing a totally endoscopic and/or robotic CABG, thoracoscopic IMA takedown would be a prerequisite. We found that injecting blood directly into normal tendons appears safe. Metabolism of drugs into clinically active compounds indicates an extra target of therapeutic drug monitoring. Reproductive endocrinology: BMPR-2 signalling is essential for maintenance of pregnancy.

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While both proteins could transport various amino acids into yeast or Arabidopsis cells, ZmAAP4 appeared to have higher efficiencies than ZmVAAT3 in transporting seven out of 22 examined amino acids. A 40-year-old male Nigerian with end-stage renal disease (ESRD) received a renal allograft from a live related donor, in the United Kingdom in 1986. Results of the present studies suggest that nicotine reduction is likely to have a large impact on nicotine exposure from cigarettes. Pyrolysis of cannabinoids: a model experiment in the study of cannabis smoking.

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In addition, two alternative channels (channels B and C) were shown to be possible pathways for ligand egression. dollars (USD) 0.57 per capita per year with a financial cost of USD0.37 per capita.

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In many cases particular research problems and specific cell types do not leave a choice for a broad variety of usable assays. A review of 734 patients in treatment for opioid addiction, who were registered to a single, specialised primary care practice in Middlesbrough, England. These data suggest that serotonin agonists might be effective only when progesterone has had sufficient time to induce sexual receptivity.

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The Israeli MoH involved the main players in the hospital market in the consolidation of this potentially controversial reform in order to avoid opposition. Effects of olfactory tract lesions on sexual and feeding behavior in the goldfish. The purpose of this study was to develop intraperitoneal hyperthermic therapy based on magnetic fluid hyperthermia, nanoparticle-wrapped cisplatin chemotherapy, and magnetic particles of albumin. Involvement of the middle third of the corona radiata, the ICAL, the ICG, and the lentiform nucleus were associated with sensory recovery. In bilaterally pseudophakic patients with a near exophoria angle of more than 12 prism diopters, we should be concerned about the possibility of variations in ocular deviation and stereopsis after cataract surgery.

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Wound healing continues to be a major burden to patients, though research in the field has expanded significantly. EC may have clinical use as a chemopreventive agent that prevents cisplatin ototoxicity. The aim of this study was to investigate the anti-fatigue activity of polysaccharides from Ziyang green tea. A histopathologic and histobacteriologic study of 35 periapical endodontic surgical specimens.

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Consequently, at a similar clay loading, the PU/D-clay nanocomposite has much higher storage modulus than the PU/organoclay nanocomposite at elevated temperatures. But the relationship between eating behavior and gender roles remains unclear.