Trazodone is a medication that possesses antidepressant, anxiolytic, and hypnotic properties. Its mechanism of action includes blockade of serotonin type 2 receptors, weak inhibition of serotonin reuptake, blockade of histamine 1 receptors, and blockade of alpha-1-adrenergic receptors. We present a case of intentional ingestion of an estimated 2500 mg of Trazodone leading to persistent hypotension, requiring aggressive fluid resuscitation, pressor support, and intensive care unit admission. Complications associated with Trazodone overdoses are significant and clinicians should be aware of the associated symptoms and necessary management plans necessary for such ingestions.
Other names for this medication:
Trazodone,
Desyrel,
Azona,
Donaren,
Mesyrel,
Nestrolan,
Oleptro,
Reslin,
Trant,
Trazodon,
Trazodona,
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Contix,
Primadex,
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Ipproton,
Arcolane,
Pepticum,
Beclabuvir,
Lanzopral,
Dutas,
Nefazan,
Nolpaza,
Aldozone,
Levunid,
Zepoxin,
Verospiron,
Noritren,
Lanzol,
Bioprazol,
Resteclin,
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Joint associations between disaster experience and age at the time of disaster on depression and post-traumatic stress disorder (PTSD) were evaluated. CD8 and CD4 T cells have a beneficial effect on the papaverine dosage forms of spironolactone course of influenza A virus infection and can recognize conserved IAV epitopes.
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